Elite’s proprietary abuse-deterrent technology, ART™, is a multi-particulate capsule that contains an agonist in addition to naltrexone, an antagonist, used primarily in the management of alcohol dependence and drug dependence. When this product is taken as intended, the naltrexone is designed to pass through the body unreleased while the agonist releases over time, providing therapeutic pain relief for which it is prescribed. If the multi-particulate beads are crushed or dissolved, the antagonist, naltrexone, is designed to release. The absorption of the naltrexone is intended to block the euphoria by preferentially binding to the same receptors in the brain as the agonist, thereby reducing the incentive for abuse or misuse by recreational drug abusers. Elite’s pharmacological approach to abuse-deterrence can be applied to a wide range of drugs used today in pain management.
